Factors affecting naltrexone metabolism include liver function, as impaired liver function can slow down its processing, prolonging its stay in the system. Genetic makeup also plays a role, with some individuals possessing higher enzymatic activity for faster metabolism. Naltrexone is available as a daily dose in a pill form (ReVia and Depade) or as a monthly intramuscular injection (Vivitrol) for treating alcohol and opioid use disorders. Naltrexone is considered unique to other substance use disorder medications because it treats both opioid and alcohol use disorders.
What Is the Washout Period for Contrave?
- At Safe Haven Recovery in Beverly Hills, California, we believe in offering the best treatment for substance abuse.
- Blood tests are slightly more invasive than saliva tests, albeit only minimally.
- For instance, the injectable form of naltrexone, known as Vivitrol, is designed to release the medication slowly over a month, providing sustained therapeutic effects.
- Understanding these differences in half-life between formulations is essential for optimizing treatment strategies and ensuring effective management of substance use disorders.
- This genetic variation is one reason why some people need different dosing frequencies to maintain effectiveness.
For those who are involved in drug abuse, addiction treatment is needed. Half life is a measure of how long it would take half of a dose of a drug to be processed and eliminated. For naltrexone, the average elimination half-life of naltrexone is between 4 hours and 13 hours. Additionally, a multitude of personal factors like age, chronic illness, body mass, hydration, and metabolism https://gamebullz.com/why-does-my-brain-feel-like-mush-causes-solutions-3/ can all impact how long naltrexone lasts in your system.
Does Contrave Stop Working After a While?

At Altitude Recovery, we’re here to elevate you from the challenges of substance use to a place of lasting resilience and renewal. Substance abuse Our dedicated team crafts personalized, evidence-based treatment plans through our comprehensive treatment services, guiding you on a journey uniquely tailored to your needs and goals. For those requiring intensive care, consider our residential inpatient program. Reach out for the compassionate support you deserve on your path to wellness by contacting us.
Factors That Affect How Long Naltrexone Stays in Your Body
If you’re over 65, you might find that naltrexone stays in your system 25-50% longer than the standard timeline. This isn’t necessarily problematic, but it’s important to discuss with your healthcare provider, especially if you’re taking other medications. This medication serves two primary purposes in addiction treatment.
Urine, Blood, and Hair Tests
Originally developed in the 1960s, naltrexone has gained prominence as a critical component in addiction treatment protocols. Naltrexone treatment is started after you are no longer taking opioids for a period of time. Before you start taking this medicine, be sure to tell your healthcare provider if you think you are still having withdrawal symptoms. Naltrexone medication works by blocking the brain’s endorphin receptors, indirectly limiting the release of dopamine after alcohol consumption. This can help individuals cut back on drinking because it makes drinking less pleasurable. When drinking on naltrexone, it’s less likely that dopamine levels will ramp up and that you’ll continue drinking to excess once you’ve started.


Generally, oral doses can last anywhere from 20 to 78 hours, while the extended-release injectable form, Vivitrol, can have effects lasting up to a week after a single injection. Naltrexone, a medication used to treat opioid and alcohol use disorder, begins to block the effects of opioids and alcohol within one to two hours. Naltrexone is prescribed to help keep you from misusing opioids again. It helps reduce the rewarding feelings you may get from taking opioids and the cravings you may have for these drugs. It’s naltrexone side effects prescribed as one part of a treatment program that may include counseling, psychotherapy, education, and support groups. Naltrexone is prescribed after you’ve stopped taking opioids or drinking alcohol to help keep you from misusing these drugs again.
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